Companies in this industry engage in biotechnology research and development to produce processes or prototypes of new or genetically altered products using microorganisms and cellular and biomolecular techniques.

Global R&D expenses for the top biotechnology regions — the US and Europe — are about $40 billion, according to Ernst & Young. Among countries, South Korea allots more than 20% of its public R&D expenditures to biotech; Germany, about 18%, and Spain, 13%, according to the World Economic Forum. About two-thirds of biotech research expenditures are for health applications.

The US biotechnology research services industry includes about 3,900 establishments (single-location companies or units of multi-location companies) with combined annual revenue of about $21 billion. The industry does not include manufacturers or contract research organizations that test products for market.

Here’s a snapshot of select publicly listed biotechnology companies:

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